Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

Nicolas Pythoud (1) , Joanna Bons (1) , Geoffroy Mijola (2) , Alain Beck (2) , Sarah Cianférani (1) , Christine Carapito (1)

1 DSA-IPHC - Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires
2 CIPF - Centre d'Immunologie Pierre Fabre

Domaines: Sciences du Vivant [q-bio]

Nicolas Pythoud, Joanna Bons, Geoffroy Mijola, Alain Beck, Sarah Cianférani, et al.. Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products. Journal of Proteome Research, 2020, ⟨10.1021/acs.jproteome.0c00664⟩. ⟨hal-02965173⟩