Could CTA be a reliable alternative method to identify non-genotoxic substances in Food Contact Material extract ?

Théo Lacour (1, 2) , Ruzanna Hayrapetyan (3) , Isabelle Séverin (3) , Isabelle Mouche (1) , Francis Finot (1) , Marie-Christine Chagnon (3)

1 GenEvolutioN
2 EPHE - École Pratique des Hautes Études
3 Derttech Packtox

In this work the objective is to minaturize the classical Cell Transformation Assay. In a second step, the aim is to etablish a more specific and sensitive labeling of transformed foci. Finally we would like to identify transcriptomics markers impacted by a Non-intentionally added substances (NIAS).

Domaines: Alimentation et Nutrition; Toxicologie et chaîne alimentaire

Théo Lacour, Ruzanna Hayrapetyan, Isabelle Séverin, Isabelle Mouche, Francis Finot, et al.. Could CTA be a reliable alternative method to identify non-genotoxic substances in Food Contact Material extract ?. ICT 2022 The XVIth International Congress of Toxicology, Sep 2022, Maastricht, Netherlands. , 368, pp.S141, 2022, ⟨10.1016/j.toxlet.2022.07.402⟩. ⟨hal-03819008⟩