Can Conjugated Linoleic Acid (CLA) safely help fighting against obesity ?

Abstract : Among the conjugated linoleic acid (CLA) isomer 10t,12c-CLA is nutritionally and commercially attractive since it has anti-obesity effects. However, this fatty acid triggers in mice a drastic decrease in adipose tissue mass, which is associated with side effects such as insulin resistance, hepatic steatosis and cholelithiasis risk. The aim of this review is to understand mechanisms responsible for these effects observed in mice and consider their existence in humans.
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Submitted on : Thursday, November 8, 2018 - 11:29:43 AM
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Hélène Poirier, Isabelle Niot, Philippe Besnard. Can Conjugated Linoleic Acid (CLA) safely help fighting against obesity ?. Obésité, Springer Verlag, 2013, 8 (1), pp.40 - 49. ⟨10.1007/s11690-012-0352-7⟩. ⟨hal-01916099⟩

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